CA2+ MOBILIZATION-DEPENDENT REDUCTION OF THE ENDOPLASMIC RETICULUM LUMEN IS DUE TO INFLUX OF CYTOSOLIC GLUTATHIONE

Ca2+ mobilization-dependent reduction of the endoplasmic reticulum lumen is due to influx of cytosolic glutathione

Abstract Background The lumen of the endoplasmic reticulum (ER) acts as a cellular Ca2+ store and a site for oxidative protein folding, which is controlled by the reduced glutathione (GSH) and glutathione-disulfide (GSSG) redox pair.Although depletion of luminal Ca2+ from the ER provokes a rapid and reversible shift towards a more reducing poise in

read more




Dashed line relaxing retinotomy in the management of retinal detachment with anterior proliferative vitreoretinopathy

Chui-Lien Tsen,1 Yu-Harn Horng,1 Shwu-Jiuan Sheu1,2 1Department of Ophthalmology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; 2School of Medicine, National Yang-Ming University, Taipei, Taiwan Background: We describe the anatomical and functional outcomes of eyes that underwent a modified technique of relaxing retinotomy, dashed line re

read more